Sanaz Mohajeri1,2, Tedros Bezabeh1,
Scott B. King1, Omkar B. Ijare1, Gerald Y. Minuk3,
Jeremy Lipschitz4, Ian C.P. Smith1
1National Research Council Institute
for Biodiagnostics, Winnipeg, Manitoba, Canada; 2Human Anatomy and
Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada; 3Hepatology,
University of Manitoba, Winnipeg, Manitoba, Canada; 4Surgery,
University of Manitoba, Winnipeg, Manitoba, Canada
Considering
the key role of liver in body metabolism, the study of bile composition is of
great importance. In vitro 1H
MRS of bile samples have shown diagnostic value in detecting various
hepatopancreatobiliary disorders. Given the invasive nature of this
procedure, we considered the possibility of gathering in vivo data. We present here our initial efforts to obtain bile
spectra from pigs using a 3T clinical scanner comparing the use of a Siemens
body array coil with an optimized home-built receive array coil.