Ke Nie1, Daniel Chang1, Jeon-Hor
Chen1,2, Tzh-Ching Shih1,2, Chieh-Chih Hsu2,
Orhan Nalcioglu1, Min-Ying Lydia Su1
1Tu & Yuen Center for Functional
Onco-Imaging, University of California, Irvine, Irvine, CA, United States; 2Department
of Radiology, China Medical University, Taichung, Taiwan
There
is a great interest to correlate between the density measured on MRI and
mammogram, so the established role for mammographic density may be extended
to MRI-based density. One problem specific to volumetric MRI analysis is the
inclusion of skin as the dense tissue. In contrast this effect could be
ignored on projection mammogram. In this study, we investigated the
correlation between the volume of the skin and the breast on 3D MRI. We
further provided two correction models aiming to provide an estimation of the
skin volume and its effect on MRI based density measurement.