Iris Y. Zhou1,2, April Mei Kwan Chow1,2,
Kevin C. Chan1,2, Condon Lau1,2, Ed X. Wu1,2
1Laboratory of Biomedical Imaging and
Signal Processing, The University of Hong Kong, Pokfulam, Hong Kong SAR,
China; 2Department of Electrical and Electronic Engineering, The
University of Hong Kong, Pokfulam, Hong Kong SAR, China
In
the present study, we use in vivo
MEMRI to detect the cerebellar activation in mouse brain induced by voluntary
wheel running. The preliminary result of our study shows that after voluntary
wheel-running exercise, mouse cerebellum regions such as vermis, Crus I and
II of ansiform lobule and caudal pontine reticular nucleus are significantly
activated compared to the sedentary animals. This difference can be feasibly
detected by MEMRI, suggesting the great potential of MEMRI as an in vivo
probe for mapping neural activity.