Maite
Aznarez-Sanado1, Maria Asuncion Fernandez-Seara1,
Federico Villagra1, Francis R. Loayza1, Jaione Irigoyen1,
Gonzalo Arrondo1, Elena Erro2, Maria Asuncion Pastor1
1Neuroscience, Center for Applied
Medical Research. University
of Navarra, Pamplona, Navarra, Spain; 2Servicio de Neurologa,
Hospital de Navarra, Pamplona, Navarra
We
aimed to study using fMRI differences in neural patterns during motor
sequence learning and automatic performance in Parkinsons disease (PD)
patients. The comparison of the early learning phase in the PD group with the
control group revealed increased activity in cortical and cerebellar areas
and right putamen in the PD group. The most affected hand recruited
contralateral basal ganglia more significantly than the non affected hand in
the PD group.