Ashu Bhasin1, Senthil S. Kumaran2,
M.V. Padma1, Sujata Mohanty3, Rohit Bhatia1
1Department of Neurology, All India
Institute of Medical Sciences, New Delhi, India; 2Department of
N.M.R., All India Institute of Medical Sciences, New Delhi, Delhi, India; 3Stem
Cell Facility, All India Institute of Medical Sciences, New Delhi, India
Autologous
mesenchymal stem cells were infused intravenously in chronic stroke patients
with a dose of 5 x 10 8 cells through median cubital vein in 4-6
hours. The experimental group was treated with stem cells and a focused
physiotherapy regime and the control group with only physiotherapy regime. It
was observed that stem cell transplantation leads to therapeutic benefits as
measured on clinical (fugel meyer & barthel index ) and functional
markers (BOLD, DTI) augmenting neural plasticity.