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Abstract #4389

Cortical Development in Children Between 6 and 11 Years

L. Tugan Muftuler1, Kevin Michael Head2, Claudia Buss2, Orhan Nalcioglu1, Curt A. Sandman2, Elysia Poggi Davis2

1Center for Functional Onco-Imaging, University of California, Irvine, CA, United States; 2Psychiatry & Human Behavior, University of California, Orange, CA, United States


There is evidence that various cognitive and psychiatric disorders might stem from abnormal cerebral development during childhood. Therefore, understanding normal cortical development is important to study these abnormalities. For that purpose, we analyzed high resolution MRI images from 129 normally developing children between ages 6 and 11 years. Cortical development between 6 an 11 years as well as within 2 year windows was investigated. The results demonstrated that the cortical development was expressed in different anatomical locations within each time frame. The findings reveal the cortical development in a much finer spatial and temporal detail than has been previously reported.