Memi
Watanabe1, Osamu Sakai1, Joseph Liao1,
Hernan Jara1,2
1Department of Radiology, Boston
Medical Center, Boston University School of Medicine, Boston, MA, United
States; 2Department of Biomedical Engineering, Boston University,
Boston, MA, United States
Purpose:
To study the aging pattern of intra- vs. extra-orbital fat tissue, using
multispectral quantitative MR imaging (qMRI). Methods: Forty-two subjects
(M:F=21:21, age: 0.5-87 years, average 31.5) were examined with experimental
mixed turbo spin echo (mixed-TSE) sequence. Region-of-interest (ROI)
measurements of retrobulbar fat, buccal fat and subcutaneous fat tissues were
obtained for multispectral qMRI analysis. Results: PD and T1 values of all
fat tissues showed similar tissue characteristics and aging patterns, while a
decrease in T1 and secular-T2 values was seen in extra-orbital fat with
aging. Conclusion: Multispectral qMRI data of aging in intra- and
extra-orbital fat tissues were obtained.