Dominique Louise Jennings1, Kim Mouridsen2,
Meiyun Wang2, Harry Miao3, Langdon Miller3,
Scott R. Plotkin4, A Gregory Sorensen2
1Department of Radiology, Athinoula A.
Martinos Center for Biomedical Imaging, Charlestown, MA , MA, United States; 2Department
of Radiology, Athinoula A. Martinos Center for Biomedical Imaging,
Charlestown, MA, MA, United States; 3PTC Therapeutics, Inc., South
Plainfield, NJ, United States; 4Department of Neurology and Cancer
Center, Massachusetts General Hospital, Boston, MA, United States
This
study applied advanced imaging techniques in the evaluation of the tumor
heterogeneity in neurofibramatosis type-2 vestibular schwannomas. We aim to
develop imaging biomarkers to assess response to anti-angiogenic therapies in
this tumor type.