Naomi
Morita1,2, Masafumi Harada1, Eva Zacharaki2,
Priyanka Bhatt2, Sanjeev Chawla2, Elias R. Melhem2,
Hiromu Nishitani1
1Radiology, Tokushima University
Hospital, Tokushima, Japan; 2Radiology, University of
Pennsylvania, Philadelphia, PA, United States
Knowledge
about microvascularity, angiogenesis or tumor cellularity is important in
determing tumor grade. The purpose of this study was to determine whether
there are any correlations between ADC, FA and rTBV value in segmented
enhancing lesion within tumor. Thirty three brain tumor patients with
contrast enhancement on MRI underwent DTI and PWI. FA, ADC and rTBV values
were measured in the segmented enhancing area within tumor. FA and rTBV had a
negative correlation (p<0.05). This study indicates that damage of fiber
and tumor progression may have any relationships in the course of tumor
progression.