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Abstract #4192

Quantification of Cell Density of SPIO-Labelled Cell Populations

Bernhard Neumayer1, Clemens Diwoky1, Andreas Reinisch2, Dirk Strunk2, Rudolf Stollberger1

1Institute of Medical Engineering, Graz University of Technology, Graz, Austria; 2Stem Cell Research Unit, Dept. of Hematology, Univ. Clinic of Internal Medicine, Medical University of Graz, Graz, Austria


The use of intracellular contrast agent suffers from quenching effects due to compartmentalization of the contrast medium inside the cell. These effects impede the correct quantification of cell populations. This study presents a simple way to quantify cell density by using inversion recovery measurements and biexponential fitting routines.