Franois
Cornelis1,2, Nicolas Grenier1,2, Chrit Moonen1,
Bruno Quesson1
1UMR 5231, Laboratory for molecular and
functional imaging, CNRS/ Universit Bordeaux 2, Bordeaux, France; 2Radiology
Department, CHU de Bordeaux, Bordeaux, France
The purpose was to evaluate in vivo
quantitatively the tissue thermal properties (perfusion, absorption, thermal
diffusivity). A
total of 42 localized HIFU heating were performed in the kidney of 6 pigs
monitored by MR thermometry. Arterial flow was modulated by an angioplasty
balloon in the aorta. The resulting temperature data were analyzed with the
Bio Heat Transfer model and an excellent correspondence was observed.
Absorption and thermal diffusivity were found independent from the flow,
whereas perfusion was directly linked to arterial flow. This method could
improve the quality of the planning of the non invasive therapy with MR
guided HIFU.