Kelvin K. Wong1,2, Hui You3,
Geoffrey S. Young3,4, Stephen TC Wong1,2
1Department of Radiology, The Methodist
Hospital Research Institute, Houston, TX, United States; 2Department
of Radiology, Weill Cornell Medical College, New York, United States; 3Department
of Radiology, Brigham and Women's Hospital, Boston, MA, United States; 4Department
of Radiology, Harvard Medical School, Boston, MA, United States
Regional
cerebral blood volume is a useful marker for brain tumor evaluation. However, large blood vessels also
contribute to high blood volume, which may have nothing to do with tumor
angiogenesis. Prior studies focused on
multi-parametric methods to remove a blood vessel which is complex to
implement and have a lot of assumptions in the automatic identifications. We
propose a simple method to identify the regions affect by large blood vessels
using a blood flow map generated by a novel deconvolution technique and
successfully identifies the blood vessel contribution in the tumor blood
volume map.