Meng Li1,
Areen Bashir1, Yanming Yu2, Yang Xuan1,
Zahid Latif1, James Garbern1, Jiani Hu1, E
M. Haacke1,3
1Wayne State University, Detroit, MI,
United States; 2Peking University, Beijing, China; 3MRI
Institute of Biomedical Research, Detroit, MI, United States
Tissue
similarity map (TSM) is a new approach to reveal the brain tissue perfusion
status directly from their signal intensity time course characteristics s(t)
rather than indirectly through the concentration time curve c(t). It avoids
the need for defining AIF as well. The purpose of this study is to use high
resolution perfusion weighted MR imaging to create a tissue similarity map to
demonstrate the differences in perfusion between tissues and inter-tissue. It
may have immediate applications in clinic.