Abstract #4010

A Minimal Model, Data-Driven Approach to Tractography

Angela Downing¹, Daniel Rueckert², A David Edwards,^1,3, Jo V. Hajnal¹

¹Robert Steiner MRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom; ²Visual Information Processing Group, Department of Computing, Imperial College London, London, United Kingdom; ³Department of Paediatrics, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, United Kingdom

We present a minimal model approach to tractography using the diffusion-weighted MRI measurements to represent samples from a diffusivity profile. Using phantom data we show that it is possible to accurately reconstruct the fibre structure between regions of interest by simulating the diffusion process that gives rise to the data.