Michel Thiebaut de Schotten1, Flavio
Dell'acqua, Dominic ffytche2, Matthew Allin3, Muriel
Walshe3, Robin Murray4, Steve Williams2,
Declan Murphy1, Marco Catani2
1Brain Maturation, Institute of
Psychiatry, London, United Kingdom; 2Centre for Neuroimaging
Sciences, Institute of Psychiatry, London; 3Department of
Psychiatry, Institute of Psychiatry, London; 4Department of
Psychological Medecine, Institute of Psychiatry, London
Increasing
knowledge of white matter organization has recently been derived from
diffusion tensor tractography but access to this knowledge has often been
limited to Diffusion Tensor Imaging (DTI) experts. Therefore a tractography
atlas of the human brain pathways is timely for a better comprehension of
brain function. However, this endeavour may be compromised by methodological
limitations of the DTI technique and the high degree of inter-individual
anatomical variability. Here we combine group effect maps with a spatial overlap
approach to develop a 3D probabilistic atlas that provides comprehensive
information about inter-subject variability and general morphology of the
tract.