Mara Cercignani1, Karl Embleton2,
Geoff J. M. Parker3, Marco Bozzali1
1Neuorimaging Laboratory, Santa Lucia
Foundation, Rome, Italy; 2Cognition and Cognitive Neuroscience
Group, School of Psychological Sciences, University of Manchester, United
Kingdom; 3Imaging Science & Biomedical Engineering and the
Biomedical Imaging Institute, University of Manchester, United Kingdom
Anatomical
connectivity mapping (ACM) is obtained by initiating tractography streamlines
from all parenchymal voxels, and counting the number of streamlines passing
through each voxel of the brain, thus highlighting WM structures strongly connected
to the rest of the brain. DTI data from 10 subjects were normalised and
averaged to compute the mean tensor, from which FA and ACM were obtained.
Colour-coded maps of principal eigenvector, modulated by ACM are displayed.
Several structures typically visible on colour-coded FA maps are visible also
on ACM. Many other structures, however, can be seen more clearly and with
greater resolution on the ACM images