Abstract #3978

Functional Diffusion Map Evaluation of Perihematomal Edema as an Imaging Biomarker for the Early Prediction of Primary Intracerebral Hemorrhage Outcome

Yuan-Hsiung Tsai^1,2, C-P Lin^2,3, L-M Hsu², H-H Weng¹

¹Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi, Taiwan, Taiwan; ²Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taipei, Taiwan, Taiwan; ³Neuroscience, National Yang Ming University , Taipei, Taiwan

This prospective study described diffusion change in perihematomal edema during acute stage (within 7 days) after primary intracerebral hemorrhage by using functional diffusion map (fDM). fDM allows a spatial, voxel by voxel tracking of changes in ADC values over time that more precisely reflect the pathophysiological heterogeneity within the edema. Using fDM to evaluate the perihematomal edema appears promising in this study. fDM is feasible in predicting clinical outcome of ICH patient during acute stage.