Min Sig
Hwang1, Katja Odening2, Ohad Ziv2, Bum-Rak
Choi2, Gideon Koren2, John R. Forder1
1McKnight Brain Institute, University of
Florida, Gainesville, FL, United States; 2Cardiovascular Research
Center, Rhode Island Hospital Alert Medical School of Brown University,
Providence, RI, United States
In
this study, we explored the potential of microscopic high angular resolution
diffusion imaging (MHARDI) achieving a cellular level spatial resolution as a
non-invasive tool that is sensitive to subtle changes in the heterogeneous
microstructure and arrangement of the cardiac tissues. Diffusion tensor images and tensor
invariants acquired with two diffusion sensitizing factors were
investigated. Our results suggest that
MHARDI with an optimized b-value and resolution may be a powerful tool for
non-invasive monitoring of electro-mechanical property and its
well-coordinated function.