Yin Wu1,2,
Ed Xuekui Wu2,3
1Institute of Biomedical and Health
Engineering, Shenzhen Institute of Advanced Technology, Shenzhen, Guangdong, China;
2Laboratory of Biomedical Imaging and Signal Processing, The
University of Hong Kong, Pokfulam, Hong Kong; 3Dept. of Electrical
and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong
Previous
DTI studies on infarcted LV
myocardium structure usually investigated diffusivity and diffusion
anisotropy. In current study, diffusion tensor shape with a combination of
linear, planar and spherical measures are examined and illustrated on a
three-phase space in porcine models. Results show that the measurements of
tensor shape have significant alteration in infarcted myocardium and are more
sensitive to detect subtle change of diffusion properties than conventionally
used parameters. Infarct location shows no apparent influence on myocardium
structural degradation. This study gives insights into myocardium structural
alteration and demonstrates potential application of DTI in detecting
infarcted heart remodeling.
