Xiao Chen1,
Xiaodong Zhong, 1,2, Frederick H. Epstein3
1Biomedical Engineering, University of
Virginia, Charlottesville, VA, United States; 2MR R&D
Collaboration, Siemens Healthcare, Atlanta, GA, United States; 3Radiology,
University of Virginia, Charlottesville, VA, United States
The
purpose of the present study was to develop a cine DENSE pulse sequence for
quantitative imaging of longitudinal motion, where two adjacent short-axis
slices are encoded for through-plane (longitudinal) displacement and are
simultaneously acquired. Displacement trajectories measured from the two
slices are used to calculate longitudinal strain. By acquiring both slices
within a single breathhold, a fixed and consistent distance between the
slices is maintained, which enables the accurate calculation of longitudinal
strain from the measured longitudinal displacement fields. The sequence and
theory were evaluated and demonstrated in normal volunteers.