Interventricular Synchrony in Chronic Thrombo-Embolic Pulmonary Hypertension Recovers After Endarterectomy

Gert Jan Mauritz¹, J. Tim Marcus¹, Jochem Bosboom¹, Anton Vonk Noordegraaf¹

The aim of this study is to assess whether the Left-Right (L-R) mechanical synchrony in Chronic Thrombo-Embolic Pulmonary Hypertension recovers after pulmonary endarterectomy. Nine patients were included, and underwent MRI myocardial tagging at baseline before, and 1 year after endarterectomy. The L-R delay in peak myocardial circumferential shortening decreased from 95 61 ms at baseline, to 2 47 ms after endarterectomy (p < 0.05). Cardiac output increased from 3.7 0.9 lit/min, to 4.8 0.6 lit/min (p<0.01). The L-R resynchronization and functional RV recovery are in line with reverse RV remodeling after endarterectomy.