Sridhar S.
Kannurpatti1, Michael Motes2, Bart Rypma2,
Bharat B. Biswal1
1Radiology, UMDNJ-New Jersey Medical
School, Newark, NJ, United States; 2Behavioral and Brain Sciences,
University of Texas at Dallas, Dallas, TX, United States
Blocked
and event related stimulus designs are typically used in fMRI studies
depending on the importance of detection power or estimation efficiency. The
extent of vascular contribution to variability in blocked and event related
fMRI-BOLD response is not known. Using
hypercapnic scaling, the extent of vascular weighting in the fMRI-BOLD
response during blocked and event related design paradigm was investigated.
BOLD data from healthy volunteers performing a block design motor paradigm
and an event related memory paradigm that needed the performance of a motor
task were analyzed from the region of interest (ROI) surrounding the primary
and supplementary motor cortices.