Fiber Diameter Mapping of a White Matter Phantom Using D-PFG Filtered MRI

Michal E. Komlosh¹, Evren Ozarslan¹, Martin J. Lizak², Ferenc Horkay¹, Peter J. Basser¹

Double pulsed field gradient spin echo (d-PFG) MRI was used to measure pore diameters in glass microcapillary arrays. Simulations, taking into account all experimental and sample parameters were used to estimate the pore diameter, which agrees very well with optical microscopy measurements. Pore distribution images suggests a potential for using this new contrast mechanism and our modeling framework to map a useful feature of local material microstructure.