Whole Brain Proton MRSI Using a Multiple 2D Sequence

Zhengchao Dong^1,2, Feng Liu^1,2, Alayar Kangarlu^1,2, Bradley Peterson^1,2

In this work, we present an extension of a widely used multi-planar MRSI sequence, which has limited brain coverage and spacing between slices. We show that by adjusting sequence parameters we can increase the number of slices without significant increase of total scan time and remove the spacing between slices without significant lose of signal-to-noise ratio. With these approaches, whole brain proton MRSI can be realized. We demonstrated the results with experimental data both on phantom and on human volunteers.