Jiang Du1, Nikolaus M. Szeverenyi1,
Sheronda Statum1, Michael Carl2, Richard Znamirowski1,
Atsushi Takahashi2, Christine Chung1, Graeme Bydder1
1Radiology, University of California,
San Diego, CA, United States; 2Global Applied Science Laboratory,
GE Healthcare Technologies, Menlo Park, CA, United States
There
are contradictory views on the T1rho relaxation mechanisms in the
literatures. In one view proton exchange between chemically shifted NH and OH
groups of PG and the tissue water might be an important relaxation mechanism.
In another view the dominant T1rho and T2 relaxation mechanism is a dipolar
interaction. Collagen fibers in tendons are highly ordered and subject to
strong dipole interactions. We proposed to use a UTE-T1rho sequence to
measure T1rho of the Achilles tendon at a series of angles and a series of
B1rho fields to investigate the contribution of dipole interaction in T1rho
relaxation mechanism.