Christina Messiou1, David Collins1,
Matthew Robson2, Veronica Morgan1, Sharon Giles1,
Catherine Parry-Jones1, Nandita deSouza1
1CRUK and EPSRC Cancer Imaging Centre,
Department of Magnetic Resonace Imaging, Institute of Cancer Research/The
Royal Marsden Hospital, Sutton, Surrey, United Kingdom; 2Department
of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
UTE
MRI allows detection of signal from very short T2 tissue that previously
returned no signal on conventional MR sequences. Preliminary data from this
ongoing study suggests that there is a significant linear relationship
between % change in T2* measured by UTE MRI and CT Hounsfield Units of
sclerotic bone metastases, hence UTE MRI has potential to quantify changes in
the sclerotic components of bone metastases. If the relationship of T2* with
HU can be extrapolated to electron density this would allow much sought after
radiotherapy planning using MR data and may also be a novel approach to
attenuation correction for PET/MR.