Frank Q. Ye1, Charles C. Zhu1,
Ning Liu2, Janita N. Turchi3, David A. Leopold1,3
1Neurophysiology Imaging Facility,
National Institute of Mental Health, NIH, Bethesda, MD, United States; 2Laboratory
of Brain and Cognition, National Institute of Mental Health, NIH; 3Laboratory
of Neuropsychology, National Institute of Mental Health, NIH, Bethesda, MD,
United States
High
resolution, high contrast MRI scans can be used in neurophysiology research
on nonhuman primates to plan invasive procedures that target deep brain
structures. With procedures involving
chronic, plastic head implants, susceptibility artifacts may severely distort
the measurement of the projected entry trajectory. Geometric distortion correction based on
field mapping is found both necessary and adequate to address this issue.