Orientation Dependence of Magnetization Transfer in Human White Matter.

Dirk K. Mller¹, Andr Pampel¹, Harald E. Mller¹

We present an investigation of the dependence of quantitative magnetization transfer (qMT) on fibre orientation. QMT parameters obtained from experiments using pulsed off-resonance irradiation were correlated to the orientation of the diffusion tensor obtained from DTI data. In particular, we observed a correlation between the fiber orientation with respect to B₀ and the transverse relaxation rate of the semi-solid pool (T_2b).