Abstract #2993

Magnetization Transfer Contrast Enhancement Due to Intermolecular Multiple Quantum Coherences - Quantitative Analysis and Tissue Dependency

Sebastian Baier¹, Stefan Kirsch¹, Lothar R. Schad¹

¹Department of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany

This work shows a quantitative analysis of magnetization transfer contrast (MTC) enhancement due to intermolecular multiple quantum coherences (iMQC). Therefore a measurement over a wide range of offset frequencies of the MT pulses was performed for different orders of iMQCs. This data was analyzed by fitting both the standard MT 2 Pool model and a modified model including the order of coherence of the iMQCs. Moreover the tissue dependency of the contrast enhancement was investigated.