Abstract #2819

Perfusion MRI of Solitary Pulmonary Nodules at 3T: Assessment of Perfusion Parameters and Correlation with Histology

Hatsuho Mamata¹, Junichi Tokuda¹, Ritu Gill¹, Robert F. Padera², Robert E. Lenkinski³, David J. Sugarbaker⁴, Hiroto Hatabu¹

¹Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; ²Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; ³Radiology, Beth Israel Decones Medical Center, Harvard Medical School, Boston, MA, United States; ⁴Thoracic surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Solitary pulmonary nodule (SPN) is one of the most common findings in chest imaging. It is important to avoid unnecessary intervention for benign lesions, thereby lowering the associated mortality / morbidity. In this study, we applied perfusion MRI to evaluate perfusion characteristics of SPN and feasibility of perfusion MRI as a diagnostic tool to differentiate malignant from benign SPN. Perfusion MRI parameters and TI curve has great potential to differentiate malignant vs. benign SPN, thus to avoid unnecessary surgical interventions.