Ryan
Alexander Priest1, Xin Li2, Ian J. Tagge2,
William J. Woodward2, Tomasz M. Beer3,4, Charles S.
Springer, Jr. 2,4, Mark G. Garzotto5,6
1Diagnostic Radiology, Oregon Health
& Science University, Portland, OR, United States; 2Advanced
Imaging Research Center, Oregon Health & Science University, Portland,
OR, United States; 3Hematology/Oncology, Oregon Health &
Science University, Portland, OR, United States; 4Knight Cancer
Institute, Oregon Health & Science University, Portland, OR, United
States; 5Urology, Oregon Health & Science University,
Portland, OR, United States; 6Portland VA Medical Center,
Portland, OR, United States
Pharmacokinetic
analysis of data generated using Dynamic-Contrast-Enhanced MRI (DCE-MRI) has
proven to be a valuable tool in the evaluation of the vascular
pathophysiology of prostate adenocarcinoma.
With improved hardware, multi-slice parametric mapping has become
feasible and could provide valuable insight to complement conventional
T2*-weighted images. In this study
multi-slice parametric mapping was performed with DCE-MRI data using both the
standard model (SM) and the first generation shutter-speed model (SSM1). Parametric maps were then compared with
biopsy results.