Ian J. Tagge1, Cecily V. Bishop2,
Richard L. Stouffer2,3, Charles S. Springer, Jr. 1, Xin
Li1
1Advanced Imaging Research Center,
Oregon Health & Science University, Portland, OR, United States; 2Division
of Reproductive Sciences, ONPRC, Oregon Health & Science University; 3Department
of Obstetrics and Gynecology, Oregon Health & Science University
The
female uterus and ovary are among the few normal tissues to undergo periodic
angiogenic changes. Using a primate
model (rhesus macaque), we investigate the feasibility of DCE-MRI to quantify
blood volume fraction (vb) and contrast reagent (CR) transendothelial
permeability. The standard model with
vb (SM2) and the second generation shutter-speed model (SSM2), are used in
parallel for this effort.