Yousef Mazaheri1, Daniel B. Rowe2,
Jingbo Zhang3, Hedvig Hricak3, Jason A. Koutcher1
1Medical Physics, Memorial Sloan
Kettering Cancer Center, New York, NY, United States; 2Mathematics,
Statistics, and Computer Science, Marquette University, Milwaukee, WI, United
States; 3Radiology, Memorial Sloan Kettering Cancer Center, New
York, NY, United States
A
stretched exponential model is presented to describe intravoxel incoherent
motion (IVIM) signal. Simulations results show that the distributed diffusion
coefficient and is a dimensionless stretching parameter have tolerable CV
(<15% at 5% noise) and bias (absolute bias< 11% at 5% noise). In vivo renal data suggests that the
stretched exponential model has potential to describe the pseudo-diffusion
behavior at low b-values.