Gavin Hamilton1, Michael S. Middleton1,
Takeshi Yokoo1, Masoud Shiehmorteza1, Claude B. Sirlin1
1Department of Radiology, University of
California, San Diego, San Diego, CA, United States
We
examined the repeatability of the liver fat fraction given by MR
Spectroscopy. We measured the fat
fraction at 3T in vivo by collecting five single average STEAM spectra at
progressively longer of TEs of 10, 15, 20, 25 and 30 ms in a single
breath-hold to generate T2 and T2-corrected peak areas. We repeated this
measurement three times per subject and showed this method produced highly
repeatable liver fat fraction and water T2 estimates. This method did not produce a repeatable
estimate of fat T2.