Choon Hua Thng1, Tong San Koh2,
Septian Hartono1, Puor Sherng Lee1, Keiko Miyazaki3,
David Collins3, Martin O. Leach3, Val Lewington4,
Dow-Mu Koh4
1National Cancer Centre Singapore,
Singapore, Singapore; 2Nanyang Technological University,
Singapore, Singapore; 3CRUK-EPSRC Cancer Imaging Centre, Institute
of Cancer Research, Sutton, United Kingdom; 4Royal Marsden NHS
Foundation Trust, Sutton, United Kingdom
Neuroendocrine
liver metastases have been described as being hypervascular in nature,
showing arterial enhancement and washout. However, other enhancement patterns
have been observed in clinical practice (plateau and progressive
enhancement). Three types of enhancement curves in neuroendocrine tumor was
found: (1) Rapid increasing followed by decrease, (2) Rapid increasing
followed by plateau, and (3) Progressively increasing. Type I pattern show
higher intravascular volume (v1) compared to percentage of interstitial
volume (v2). Type II and III pattern show higher v2 compared to v1. Type I
pattern show higher blood flow (F) compared to Type II/III.