Gregory Jacques Ramniceanu1, Erez Eyal2,
Inbal Biton3, Nava Nevo2, Raanan Margalit4,
Raya Eilam-Altstadter3, Hadassa Degani1
1Biological regulation, Weizmann
Institute of Science, Rehovot, Israel; 2biological regulation,
Weizmann Institute of Science, Rehovot, Israel; 3Veterinary
Resources, Weizmann Institute of Science, Rehovot, Israel; 4Immunology,
Weizmann Institute of Science, Rehovot, Israel
The
lung vasculature is composed of two systems, the bronchial and the pulmonary
circulations. It is still unknown which of these two circulations, or both,
contribute to the feeding of lung tumors during their progression .To answer
this basic we characterize the perfusion parameters and the role of
angiogenesis and interstitial fluid pressure in the lung tumors using MRI and
optical imaging methods. Specifically we focus on imaging interstitial fluid
pressure using a slow infusion protocol of the contrast agent.