Elena
Shumskaya1,2, Teuntje Andriessen2, David Norris1,3,
Pieter Vos2
1Donders Institute for Brain, Cognition
and Behaviour, Radboud University Nijmegen, Nijmegen, Gelderland,
Netherlands; 2Department of Neurology, Radboud University Nijmegen
Medical Centre, Nijmegen, Gelderland, Netherlands; 3Erwin L. Hahn
Institute for Magnetic Resonance, Essen, Germany
The
objective of this study is to evaluate the alterations in the whole-brain
functional connectivity after fronto-occipital impact mild traumatic brain
injury (MTBI). We used the resting state fMRI to relate the cognitive
deficits occurring after frontal-occipital impact MTBI to the disruptions in
functional connectivity. We found the disintegration of prefrontal, temporal
and parietal regions in resting-state networks of MTBI patients and showed
that the disconnection between prefrontal regions underlies the decline in
the rate of information processing.