Pim van Ooij1, Annetje Gudon2,
Christian Poelma3, Joppe J. Schneiders4, Charles B.
Majoie4, Jenny Dankelman2, Ed vanBavel1,
Aart J. Nederveen4
1Biomedical Engineering & Physics,
Academic Medical Center, Amsterdam, Noord-Holland, Netherlands; 2Biomechanical
Engineering, Delft University of Technology, Delft, Netherlands; 3Laboratory
for Aero and Hydrodynamics, Delft University of Technology, Delft,
Netherlands; 4Radiology, Academic Medical Center
To
validate 4D blood flow velocity measurements in intracranial aneurysms using
phase contrast MRI, a real-size glass phantom of an intracranial aneurysm was
created and used for blood flow velocity measurements using PC-MRI and PIV.
Resolution of PC-MRI was 0.5x0.5x0.5 mm and took 70 minutes to scan. Both
steady and pulsatile flow measurements in MRI and PIV produced similar flow
patterns of similar magnitude, although more noise was found in the MR
results. Velocity to noise ratio will improve with more accurate velocity
encoding settings. More importantly, to be able to apply the PC-MRI scan in
patients, scan time needs to be shortened severely, for example by
acceleration techniques.