Naoki Ohno1,2, Tosiaki Miyati2,
Mitsuhito Mase3, Hirohito Kan2, Harumasa Kasai4,
Masaki Hara4, Yuta Shibamoto4, Kazuo Yamada3,
Akihiro Kitanaka2, Tomoyuki Yamamoto1
1Department of Radiological Technology,
Kanazawa University Hospital, Kanazawa, Japan; 2Faculty of Health
Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa
University, Kanazawa, Japan; 3Department of Neurosurgery and
Restorative Neuroscience, Graduate School of Medical Sciences, Nagoya City
University, Nagoya, Japan; 4Department of Radiology, Nagoya City
University Hospital, Nagoya, Japan
There
have been many unsolved problems with this syndrome in terms of the
diagnostic criteria and selection of appropriate patients for shunt surgery.
To evaluate the intracranial condition of the brain in idiopathic
normal-pressure hydrocephalus (I-NPH), we determined the change in the
apparent diffusion coefficient of the brain during the cardiac cycle
(delta-ADC). Delta-ADC analysis makes it possible to noninvasively obtain new
and more detailed information on the intracranial condition in I-NPH and
thereby assist in the diagnosis.