Abstract #2227

Quantitative Magnetization Transfer Imaging in Acute Stroke: A Follow Up Study Correlating Quantitative MRI with Respect of Severity of Stroke

Felix Jax¹, Monika Gloor², Oliver Bieri², Meritxell Garcia¹, Stefan Engelter³, Felix Fluri³, Klaus Scheffler², E.-W. Radue¹, SG Wetzel¹

¹Department of Neuroradiology, University of Basel Hospital, Basel, Switzerland; ²Department of Radiological Physics, University of Basel Hospital, Basel, Switzerland; ³Department of Neurology, University of Basel Hospital, Basel, Switzerland

Magnetisation transfer (MT) imaging can potentially serve as a marker for loss of tissue integrity. Moreover increased pathologic specificity is expected from quantitative MT (qMT) as compared to the assessment of the semi-quantitative MT ratio (MTR) images only. Here, we present an evaluation of qMTI data over three consecutive MRIs within the first 10 days for patients suffering from middle cerebral artery stroke with different progression of symptoms. Results seem to be superior to simple MTR measurements and possibly allow for early statement of prognosis and efficacy of therapeutic methods.