Timothy Lloyd Jones1, Ai Wern Chung2,
Andrew John Lawrence2, B Anthony Bell1, Thomas Richard
Barrick2
1Academic Neurosurgery Unit, St
George's University of London, London, United Kingdom; 2Centre for
Clinical Neurosciences, St George's University of London, London, United
Kingdom
Difficulties
can arise in clinical practice in differentiating between primary malignant
glioma and brain metastasis owing to their similar appearances on
conventional MRI sequences. Although previous studies have identified
differences in diffusion parameters between the tumour types, the diagnostic
role of diffusion tensor imaging (DTI) has yet to be fully elucidated. We
propose an application of a novel whole brain DTI segmentation algorithm in
generating regions of interest (tumour and oedema) from Diffusion Colour Maps
(DCMs) created using our technique. We identify differences in diffusion between
tumour types, compare our method with conventional manually drawn regions of
interest and propose potential clinical applications for our method.