Abstract #2109

Quantitative Venous Vasculature Assessment on Susceptibility-Weighted Imaging Reflects Presence of Severe Chronic Venous Insufficiency in the Brain Parenchyma of Multiple Sclerosis Patients. a Case-Control Study

Guy U. Poloni¹, Paolo Zamboni², E. Mark Haacke³, Stefano Bastianello⁴, Michael G. Dwyer¹, Niels Bergsland⁵, Claudiu V. Schirda¹, David Wack¹, Christopher R. Magnano¹, Bianca Weinstock-Guttman⁶, Fabrizio Salvi², David Hojnacki⁶, Robert Zivadinov¹

¹University at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, United States; ²University of Ferrera- Bellaria Neurosciences, Vascular Diseases Center, Ferrera, Italy; ³Radiology, Wayne State University, Detroit, MI, United States; ⁴Institu Neurologico Casimiro Mondino, Neuroradiology Unit, Pavia, Italy; ⁵University at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, United States; ⁶University at Buffalo, The Jacobs Neurological Institute, Buffalo, NY, United States

To develop an objective method for quantifying venous vasculature in brain parenchyma on susceptibility-weighted imaging (SWI). To apply this technique in multiple sclerosis (MS) patients and in healthy controls (HC).