Kamal Shahim1, Ralph Sinkus2,
Jean-Marie Drezet1, Shahan Momjian3, jean-francois
Molinari4
1LSMX, Ecole Polytechnique Fdrale de
Lausanne, Lausanne, Vaud, Switzerland; 2Laboratoire Ondes et
Acoustique, ESPCI, Paris, France; 3University Hospitals of Geneva
and University of Geneva, Switzerland; 4LSMS, Ecole Polytechnique
Fdrale de Lausanne, Lausanne, Vaud, Switzerland
Hydrocephalus
is a cerebral disease wherein the brain ventricles dilate and the parenchyma
is stressed. In order to study this condition, a finite element model is
built using the geometries of the ventricles and the skull measured by MRI.
DTI is used to establish the fiber direction and the local frame. Indeed,
elasticity data based on MRE is incorporated into the constitutive equation.
The brain parenchyma is modeled as a porous medium. Under an applied pressure
gradient, Isotropic and Transverse Isotropic models are tested and compared
together. The transmission of the applied pressure is substantially
influenced by the anisotropy and inhomogeneity of brain parenchyma.