Diffusion MRI of in Utero Mouse Embryos

Lin Zhao¹, Scott E. Fraser¹, J. Michael Tyszka¹

In utero MR microscopy of developing mouse embryos is complicated by maternal respiratory motion and by the general lack of tissue contrast between embryonic tissues, particularly in the CNS. We explore here the use of volumetric diffusion-weighted MR microscopy to visualize the embryonic brain in utero at later development stages.