Vanessa Anne Sluming1,2, Andrew Mayes3,
Iain D. Wilkinson4, Charles Romanowski4, Enis Cezayirli5,
Patricia E. Cowell6
1School of Health Sciences, University
of Liverpool, Liverpool, Merseyside, United Kingdom; 2Magnetic
Resonance and Image Analysis Research Centre, University of Liverpool,
Liverpool, Merseyside, United Kingdom; 3School of Psychology,
University of Manchester, Manchester, United Kingdom; 4Academic
Department of Radiology, University of Sheffield, United Kingdom; 5Department
of Anatomy, University of Celal Bayar , Turkey; 6Department of
Human Communication Sciences, University of Sheffield, United Kingdom
VBM
analysis of grey matter distribution within the healthy adult brain was undertaken,
in a sample of 31 males and 35 females (age range: 20-72 years) to
investigate sex differences in the effect of brain ageing. Data were analysed
using a full factorial analysis (2x2x2). There were no significant sex by age
effects. Within sex regression analyses revealed that females showed age
related GM decrements within several frontal regions tending medially,
whereas males sowed age related decrements in bilateral structures including
IFG (BA44/45). These findings are discussed.