J. B.M.
Warntjes1,2, J. West1,3, R. Birgander4, P.
Lundberg5
1Center for Medical Imaging Science and
Visualization (CMIV), Linkping, Sweden; 2Department of Medicine
and Health, Division of Clinical Physiology, Linkping, Sweden; 3,
Department of Medicine and Health, Division of Radiation Physics, Linkping,
Sweden; 4Department of Radiology (NUS), Department of Radiation
Sciences, Ume, Sweden; 5Department of Medicine and Health,
Division of radiation physics, Linkping, Sweden
A
method is described to measure the partial volume fraction of cerebrospinal
fluid for each voxel in a complete brain volume within a scan time of 5 to 6
minutes, based on quantification of the relaxation rates R1 and R2 and proton
density. This measurement allows to accurately segment the brains ventricular
system independent of image resolution and without user-dependent image
thresholding.