Abstract #1919

3D δR2 Microscopy MRA with a New Blood Pool Contrast Agent: A Comparison with Resovist

Chien-Yuan Lin¹, Si-Han Wu², Ming-Huang Lin¹, Yann Hung², Chung-Yuan Mou², Chen Chang¹

¹Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; ²Department of Chemistry, National Taiwan University, Taipei, Taiwan

We have recently developed a new blood pool contrast agent (Fe3O4@SiO2/PEG) which possesses higher transverse relaxivity and long intravascular half-life. This study was aimed to assess the ability of Fe3O4@SiO2/PEG to improve high-resolution magnetic resonance angiography in visualizing cerebral microvasculature.