Johnathan C. Chung1, Robert K. Ryu1,
Dingxin Wang2, Richard Tang1, Reed A. Omary2,3,
Andrew C. Larson2,3
1Department of Radiology, Northwestern
University, Chicago, IL, United States; 2Department of Radiology
and Biomedical Engineering, Northwestern University, Chicago, IL, United
States; 3Robert H. Lurie Comprehensive Cancer Center, Northwestern
University, Chicago, IL, United States
Four-dimensional
(4D) transcatheter intra-arterial perfusion (TRIP) MRI is a monitoring
technique that involves targeted intra-arterial (IA) injections of gadolinium
(Gd) (<0.001 mmol/kg) to help quantify volumetric tissue-perfusion changes
over time. This technique can be used to objectively monitor tumor perfusion
changes after UAE in VX2 rabbits. The technique may have future clinical
application in optimizing endpoints during UAE.