Rebecca Susan Dewey1,2, Dorothee P. Auer1,
Susan T. Francis2
1Division of Academic Radiology,
University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Sir
Peter Mansfield Magnetic Resonance Centre, University of Nottingham,
Nottingham, Nottinghamshire, United Kingdom
Watershed
areas are brain regions supplied by the most distal branches of the cerebral
arteries and are most susceptible to haemodynamic ischaemia. We assess the use of territorial ASL to
define Left and Right Internal Carotid, Anterior Cerebral, and Basilar Artery
territories to distinguish the watershed area, and assess its correspondence
with haemodynamic parameters (perfusion rate, arterial blood volume and
arterial and tissue transit times) from multiphase ASL. Specified anatomical regions are assessed
for vascular supply and haemodynamic parameters. Combining these techniques, an atlas of
parameters can be formed for region-specific perfusion and position and
functional effects of watershed areas.