Huan Tan1,
W. Scott Hoge2, Craig A. Hamilton1, Robert A. Kraft1
1Virgina-Tech Wake Forest School of
Biomedical Engineering, Winston-Salem, NC, United States; 2Radiology,
Brigham and Women's Hosptial, Boston, MA, United States
3D
GRASE offers an inherent SNR advantage for ASL perfusion imaging over
conventional 2D EPI. However, it suffers from through-plane blurring due to
T2 decay that reduces image quality and limits spatial resolution.
Incorporating a PROPELLER trajectory into 3D GRASE reduces the ETL and
subsequently the through-plane blurring. Furthermore, a PROPELLER trajectory
is less susceptible to field inhomogeneities due to its shorter echo train
length. In summary, 3D GRASE PROPELLER improves ASL perfusion images without
increasing scan time while maintaining the perfusion SNR.